Module 3: Statistical Rigor in Bioinformatics

This module discusses the need to establish capacity for statistical significance in the context of computational reproducibility.

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Learning Objectives

Module Content

Complete the content below in order for better understanding and continuity of information.

Reading: Statistics as a Discipline

Statistics as a Discipline

Estimated time to complete: 5–15 minutes

Video: Statistics Checkpoint

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Captions and transcript available within the player.

Estimated time to complete: 10 minutes

Reflection: Your Statistical Foundation

Reflect on the following question(s) before moving on:

  1. Are you confident in your ability to justify your project or hypothesis statistically?
  2. Do you feel confident in your grasp of the need for statistical rigor?

Estimated time to complete: 5–10 minutes

Activity: Basic Statistics Checkpoint
Activity: Basic Statistics Checkpoint

Estimated time to complete: 5–10 minutes

Video: Statistical Rigor

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Captions and transcript available within the player.

Estimated time to complete: 10 minutes

Activity: Basic Inferential Statistics Checkpoint
Activity: Basic Inferential Statistics Checkpoint

Estimated time to complete: 5–10 minutes

Reading: Federal Funding Expectatons for Rigor

Federal Funding Expectatons for Rigor

Estimated time to complete: 5–15 minutes

Activity: What is the Appropriate Statistical Test?
Activity: What is the Appropriate Statistical Test?

Estimated time to complete: 5–10 minutes

Resources: More Help with Statistics

There are multiple ways you can get additional, free online support for statistical rigor. Many people need support with statistics - do not hesitate to ask for help. The rigor of your project depends on it!

Free Basic Support for Choosing the Right Test

  1. Statistical Test Selection Tool
  2. Choosing the Correct Statistical Test
  3. Flow Chart for Selecting Commonly Used Statistical Tests
  4. An Introduction to Statistics: Choosing the Correct Statistical Test
  5. Clearinghouse for Modules to Enhance Biomedical Research Workforce Training

Free Online Learning Resources

  1. OpenStax Introductory Statisticcs 2e
  2. Khan Academy Statistics Playlist
  3. Coursera Statistics Courses
  4. Open Learning Initiative - Probability & Statistics — Open & Free Course

Estimated time to complete: 20-30 minutes

Next Steps
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