Module 4: Reliability, Generalizability, & Robustness in Bioinformatics

This module discusses the need to understand other ways to examine the scientific reproducibility of computational analyses in biomedical research.

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Learning Objectives

Module Content

Complete the content below in order for better understanding and continuity of information.

Reading: Other Metrics of Scientific Rigor and Reproducibility

Other Metrics of Scientific Rigor and Reproducibility

Estimated time to complete: 10–25 minutes

Video: Generalizability

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Estimated time to complete: 15 minutes

Reading: Consider Generalizability

Reading: Consider Generalizability

Estimated time to complete: 15–25 minutes

Video: Robustness, Reliability, and Repeatability

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Estimated time to complete: 15 minutes

Video: Repeatability

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Estimated time to complete: 15 minutes

Video: Framing your Scope

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Estimated time to complete: 15 minutes

Reflection: Reliability, Generalizability, & Robustness

Reflect on the following questions before moving on:

  • Think about a scientific result you have heard about in the news or in class. What information would you need to determine whether the result is reliable and robust?
  • Consider a study that uses data from a small group of individuals or a single population. What factors might limit the generalizability of the findings to broader populations? What are the important reasons for performing studies with limited generalizability?

Estimated time to complete: 15–25 minutes

Practice Quiz: Module Overview

Practice Quiz: Module Overview

Estimated time to complete: 15–25 minutes

Next Steps
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